Utilization of Brain Imaging Data and Quantification in FinnGen and Biobank Data – The ’IMAGEN-BRAIN’ Study
21.08.2024
In this study, we establish a protocol for the use and quantitative analysis of neuroradiological images of interest identified from biobank data as part of precise disease characterization and prognostic assessment. Additionally, we investigate the availability of neuroradiological imaging studies (brain CT and MRI scans) in the biobank data. We also investigate the effect of the APOE4 genotype on the values produced by structural analysis of the brain and examine the relationship between structural brain changes and blood biomarkers for a subset of the cohort.